3' UTR Citations

OriGene产品已被全世界的科学家广泛使用,以提高他们的研究效率。 为了供您参考,我们收集了一些使用OriGene产品发表过的代表性的引用文献,将其发布在此页面上。

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这是研究人员使用OriGene产品后最新发表的一些论文。

靶点 研究论文 杂志 产品类型 货号
14-3-3 zeta Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer Oncogene 3' UTR SC217826
ABCG1 Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRa expression and cholesterol homeostasis Cell Death and Disease 4, e780 doi:10.1038/cddis.2013.301 3' UTR SC210681
ACACA MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 Sci Rep 3' UTR SC218496
ACAP1 A Brucella effector modulates the Arf6‐Rab8a GTPase cascade to promote intravacuolar replication The EMBO Journal 3' UTR SC200526
ACOT7 Novel miRNA-31 and miRNA-200a-Mediated Regulation of Retinoblastoma Proliferation PLoS ONE 3' UTR SC204439
ACTR3 Actin related protein 3 (ARP3) promotes apoptosis of intestinal epithelial cells in ulcerative colitis. Pathology, research and practice 3' UTR SC212790
ADAM12 ADAM12-L is a direct target of the miR-29 and miR-200 families in breast cancer BMC cancer 3' UTR SC220027
ADAM12 MULTIPLE ISOFORMS OF ADAM12 IN BREAST CANCER: DIFFERENTIAL REGULATION OF EXPRESSION AND UNIQUE ROLES IN CANCER PROGRESSION Thesis 3' UTR SC220027
ADAM17 Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells Sci Rep 3' UTR SC211049
AGO3 An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron Science translational medicine 3' UTR SC209419
ALDH1B1 Human ALDH1B1 polymorphisms may affect the metabolism of acetaldehyde and all- trans retinaldehyde – in vitro studies and computational modeling Pharmaceutical research 3' UTR SC214246
ALDH1B1 Aldehyde Dehydrogenase 1B1: Molecular Cloning and Characterization of a Novel Mitochondrial Acetaldehyde-Metabolizing Enzyme Drug Metabolism and Disposition 3' UTR SC214246
ALDOC BCDIN3D RNA methyltransferase stimulates Aldolase C expression and glycolysis through let-7 microRNA in breast cancer cells Oncogene 3' UTR SC205743
AMHR2 Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Oncotarget 3' UTR SC200131
Amyloid Precursor Protein MiRNA-31 improves cognition and abolishes amyloid-β pathology by targeting APP and BACE1 in an animal model of Alzheimer’s disease Molecular Therapy - Nucleic Acids 3' UTR SC212695
APOL1 Exon 4-encoded sequence is a major determinant of cytotoxicity of apolipoprotein L1 American Journal of Physiology - Cell Physiology 3' UTR SC215050
AREB6 miR-200c inhibits the arecoline-associated myofibroblastic transdifferentiation in buccal mucosal fibroblasts J. Formos. Med. Assoc. 3' UTR SC219122
ARHGDIA Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer Oncogene 3' UTR SC213168
ARSB miR-154-5p Functions as an Important Regulator of Angiotensin II-Mediated Heart Remodeling Oxidative Medicine and Cellular Longevity 3' UTR SC207651
ATF1 Long non-coding RNA RP11-552M11.4 favors tumorigenesis and development of cervical cancer via modulating miR-3941/ATF1 signaling Int. J. Biol. Macromol. 3' UTR SC214060
ATF6 PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response Sci Rep 3' UTR SC205479
ATF6 miRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6 Molecular and Cellular Pediatrics 3' UTR SC205479
ATG5 MiR-216a: a link between endothelial dysfunction and autophagy Cell Death Dis, Jan 2014. 3' UTR SC217570
ATP6AP2 MicroRNA-152 represses VEGF and TGFß1 expressions through post-transcriptional inhibition of (Pro)renin receptor in human retinal endothelial cells Mol. Vis. 3' UTR SC210837
Aurora A Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition Oncotarget 3' UTR SC209773
AXL The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels PLoS ONE 3' UTR SC216808
BCL2 miR-185-5p response to usnic acid suppresses proliferation and regulating apoptosis in breast cancer cell by targeting Bcl2 Biol. Res. 3' UTR SC200550
Beclin 1 mda-7/IL-24 Mediates Cancer Cell-Specific Death via Regulation of miR-221 and the Beclin-1 Axis Cancer Res 3' UTR SC208275
Beclin 1 MiR-216a: a link between endothelial dysfunction and autophagy Cell Death Dis, Jan 2014. 3' UTR SC208275
BMI1 Regulation of miRNA biogenesis and histone modification by K63-polyubiquitinated DDX17 controls cancer stem-like features Cancer Res. 3' UTR SC217171
BMI1 Hinokitiol up-regulates miR-494-3p to suppress BMI1 expression and inhibits self-renewal of breast cancer stem/progenitor cells Oncotarget 3' UTR SC217171
BMI1 miR-494-3p Induces Cellular Senescence and Enhances Radiosensitivity in Human Oral Squamous Carcinoma Cells Int J Mol Sci 3' UTR SC217171
BMI1 MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells Neuro Oncology, Jun 2013; 10.1093/neuonc/not055. 3' UTR SC217171
BORIS MicroRNA-193a Downregulates HMGB1 to Alleviate Diabetic Neuropathic Pain in a Mouse Model Neuroimmunomodulation 3' UTR SC214474
BORIS miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration Sci Rep 3' UTR SC214474
BRD7 Angiotensin II type I receptor and miR-155 in endometrial cancers: synergistic antiproliferative effects of anti-miR-155 and losartan on endometrial cancer cells. Gynecologic oncology 3' UTR SC202420
BRD7 The interactions between MicroRNA-200c and BRD7 in endometrial carcinoma. Gynecologic oncology 3' UTR SC202420
c Fos MicroRNA-365 targets multiple oncogenes to inhibit proliferation, invasion, and self-renewal of aggressive endometrial cancer cells CMAR 3' UTR SC210084
c-Myc MicroRNA Regulation of Mitogenic Signaling Networks in the Human Placenta J. Biol. Chem. July 2014 3' UTR SC206606
CARM1 Oxidative stress destabilizes protein arginine methyltransferase 4 via glycogen synthase kinase 3β to impede lung epithelial cell migration American Journal of Physiology - Cell Physiology 3' UTR SC211820
CASP5 Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization Immunity 3' UTR SC200800
Caspase 9 Novel Anti-Apoptotic MicroRNAs 582-5p and 363 Promote Human Glioblastoma Stem Cell Survival via Direct Inhibition of Caspase 3, Caspase 9, and Bim PLoS ONE 3' UTR SC208909
CBLB miR-1323 Promotes Cell Migration in Lung Adenocarcinoma by Targeting Cbl-b and Is an Early Prognostic Biomarker Front. Oncol. 3' UTR SC209114
CCK4 MiR‐503 pleiotropically regulates epithelial‐mesenchymal transition and targets PTK7 to control lung cancer metastasis Cancer Medicine 3' UTR SC210336
CCN2 MicroRNA-26a inhibits TGF-ß-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy Diabetologia 3' UTR SC212423
CD163 MicroRNA networks associated with active systemic juvenile idiopathic arthritis regulate CD163 expression and anti-inflammatory functions in macrophages through two distinct mechanisms J. Leukoc. Biol. 3' UTR SC208301
CD44 The Wnt modulator ICG‑001 mediates the inhibition of nasopharyngeal carcinoma cell migration in vitro via the miR‑150/CD44 axis Int. J. Oncol. 3' UTR SC220255
CDC7 p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress Cell Cycle 3' UTR SC214002
CELA1 Stretch regulates expression and binding of chymotrypsin-like elastase 1 in the postnatal lung The FASEB Journal 3' UTR SC201149
CES1 Carboxylesterases 1 and 2 Hydrolyze Phospho-Nonsteroidal Anti-Inflammatory Drugs: Relevance to Their Pharmacological Activity The Journal of Pharmacology and Experimental Therapeutics 3' UTR SC202442
CFTR Regulation of Cystic Fibrosis Transmembrane Conductance Regulator by MicroRNA-145, -223, and -494 Is Altered in F508 Cystic Fibrosis Airway Epithelium J. Immunol., Apr 2013; 190: 3354 - 3362. 3' UTR SC215270
CHEK1 Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery Human Molecular Genetics 3' UTR SC205740
CLDN14 Thick ascending limb claudins are altered to increase calciuria and magnesiuria in metabolic acidosis. American journal of physiology. Renal physiology 3' UTR SC204989
CLIP1 The cholangiocyte marker, BD. 1, forms a stable complex with CLIP170 and shares an identity with eIF3a, a multifunctional subunit of the eIF3 initiation complex Experimental and molecular pathology 3' UTR SC214695
COL17A1 Regulation of collagen type XVII expression by miR203a-3p in oral squamous cell carcinoma cells J. Biochem. 3' UTR SC211303
CRTC2 Breaking Human Cytomegalovirus Major Immediate-Early Gene Silence by Vasoactive Intestinal Peptide Stimulation of the Protein Kinase A-CREB-TORC2 Signaling Cascade in Human Pluripotent Embryonal NTera2 Cells 3' UTR SC206009
custom cJUN microRNA-200b modulates microglia-mediated neuroinflammation via the cJun/MAPK pathway J. Neurochem. April 2014 3' UTR
CXCL2 Oncosuppressive miRNAs loaded in lipid nanoparticles potentiate targeted therapies in BRAF-mutant melanoma by inhibiting core escape pathways of resistance Oncogene 3' UTR SC209527
CYB5R2 Cytochrome b5 reductase 2 is a novel candidate tumor suppressor gene frequently inactivated by promoter hypermethylation in human nasopharyngeal carcinoma Tumour Biology 3' UTR SC203570
CYP27B1 MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 Sci Rep 3' UTR SC210195
CYP2J2 Functional studies of N-terminally modified CYP2J2 epoxygenase in model lipid bilayers Protein Science : A Publication of the Protein Society 3' UTR SC204867
DEPTOR microRNA-181a downregulates deptor for TGFβ-induced glomerular mesangial cell hypertrophy and matrix protein expression Exp. Cell Res. 3' UTR SC213241
DLG4 FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain Mol Biosyst . April 2014 3' UTR SC210442
DOK4 A BRET assay for monitoring insulin receptor interactions and ligand pharmacology. Journal of receptor and signal transduction research 3' UTR SC214478
E Cadherin Severe Neonatal Anemia Increases Intestinal Permeability by Disrupting Epithelial Adherens Junctions Am. J. Physiol. Gastrointest. Liver Physiol. 3' UTR SC217485
E2F3 Epstein-Barr Virus Downregulates MicroRNA 203 through the Oncoprotein Latent Membrane Protein 1: a Contribution to Increased Tumor Incidence in Epithelial Cells Journal of Virology 3' UTR SC220669
E2F4 Establishment of the TBX-code reveals aberrantly activated T-box gene TBX3 in Hodgkin lymphoma PLoS ONE 3' UTR SC209960
E2F4 Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer Nature Communications 3' UTR SC209960
EDIL3 Expression and Function of the Homeostatic Molecule Del-1 in Endothelial Cells and the Periodontal Tissue Clinical and Developmental Immunology 3' UTR SC212505
EGLN2 Hypoxia-inducible factor-1α-dependent induction of miR122 enhances hepatic ischemia tolerance The Journal of clinical investigation 3' UTR SC207831
EGLN2 Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1 Oncogene 3' UTR SC207831
ERK2 MicroRNA Regulation of Mitogenic Signaling Networks in the Human Placenta J. Biol. Chem. July 2014 3' UTR SC201852
EZH2 MicroRNA-365 targets multiple oncogenes to inhibit proliferation, invasion, and self-renewal of aggressive endometrial cancer cells CMAR 3' UTR SC203485
FASN MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 Sci Rep 3' UTR SC210244
FKBP14 Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells Sci Rep 3' UTR SC214741
FNDC4 FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice Nature Communications 3' UTR SC207774
FOXC1 The Role of hsa-miR-548l Dysregulation as a Putative Modifier Factor for Glaucoma-Associated FOXC1 Mutations. MicroRNA (Shariqah, United Arab Emirates) 3' UTR SC216457
FOXJ3 MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and Forkhead box j3 Am J Physiol Endocrinol Metab, Dec 2012; 303: E1419 - E1427. 3' UTR SC220419
Foxo4 Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis FASEB J 3' UTR SC214742
FOXO4 Down-Regulation of miR-23b Induces Phenotypic Switching of Vascular Smooth Muscle Cells in vitro and in vivo Cardiovasc. Res. 3' UTR SC214742
GAD2 Abundant glutamic acid decarboxylase (GAD)-reactive B cells in gad-antibody-associated neurological disorders. Annals of neurology 3' UTR SC207536
GAD2 Cerebellar Ataxia and Glutamic Acid Decarboxylase Antibodies JAMA neurology 3' UTR SC207536
GAD2 Transglutaminase 4 as a prostate autoantigen in male subfertility. Science translational medicine 3' UTR SC207536
GAD2 Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice 3' UTR SC207536
GAPDH PKCe Promotes HuD-Mediated Neprilysin mRNA Stability and Enhances Neprilysin-Induced Aß Degradation in Brain Neurons PLoS ONE 3' UTR SC202241
GIT2 The lncRNA H19 mediates breast cancer cell plasticity during EMT and MET plasticity by differentially sponging miR-200b/c and let-7b. Science signaling 3' UTR SC209774
GJA1 Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival Oncogenesis 3' UTR SC216210
GLRB Inhibition of miR-203 Reduces Spontaneous Recurrent Seizures in Mice Mol. Neurobiol. 3' UTR SC215897
Glutathione Peroxidase 1 Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells Cardiovasc Diabetol 3' UTR SC202736
GOLGA2 GOLGA2/GM130, cis -Golgi Matrix Protein, is a Novel Target of Anticancer Gene Therapy Molecular Therapy 3' UTR SC213684
GRO alpha Let-7g* and miR-98 Reduce Stroke-Induced Production of Proinflammatory Cytokines in Mouse Brain Front. Cell Dev. Biol. 3' UTR SC209215
HBG1 Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells Exp. Biol. Med. (Maywood) 3' UTR SC200439
HBG2 Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells Exp. Biol. Med. (Maywood) 3' UTR SC200430
Her2 Erb-B2 Receptor Tyrosine Kinase 2 is negatively regulated by the p53-responsive microRNA-3184-5p in cervical cancer cells Oncology Reports 3' UTR SC208188
HGF MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner Journal of Hematology & Oncology 3' UTR SC206339
HIF1AN MiR-24 induces chemotherapy resistance and hypoxic advantage in breast cancer Oncotarget 3' UTR SC222457
HMGCR MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 Sci Rep 3' UTR SC216360
HOXC10 miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis Prog. Neurobiol. 3' UTR SC210839
HPF1 Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency Communications Biology 3' UTR SC201015
ICAM3 Virion-incorporated PSGL-1 and CD43 inhibit both cell-free infection and transinfection of HIV-1 by preventing virus–cell binding Proceedings of the National Academy of Sciences of the United States of America 3' UTR SC200568
IL8 Expression of miR-93 and IL-8 During Pseudomonas aeruginosa Mediated Induction of Pro-Inflammatory Responses Am. J. Respir. Cell Mol. Biol., Jan 2014. 3' UTR SC213557
iNOS Regulation of proinflammatory genes by the circulating microRNA hsa-miR-939 Sci Rep 3' UTR SC206494
iNOS MicroRNA Regulation of Proinflammatory Response in X-linked Adrenoleukodystrophy Journal of Clinical & Cellular Immunology 3' UTR SC206494
INSIG2 Overexpression of Insig-2 inhibits atypical antipsychotic-induced adipogenic differentiation and lipid biosynthesis in adipose-derived stem cells Scientific Reports 3' UTR SC216121
INSIG2 Insulin-induced gene 2 expression correlates with colorectal cancer metastasis and disease outcome. IUBMB life 3' UTR SC216121
IP10 Let-7g* and miR-98 Reduce Stroke-Induced Production of Proinflammatory Cytokines in Mouse Brain Front. Cell Dev. Biol. 3' UTR SC210131
IRAK4 Regulation of TLR2-Mediated Tolerance and Cross-Tolerance through IRAK4 Modulation by miR-132 and miR-212 J. Immunol., Feb 2013; 190: 1250 - 1263. 3' UTR SC219805
IRS2 Recurrent Amplification at 13q34 Targets at CUL4A , IRS2 , and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma PLoS ONE 3' UTR SC218912
KCNA5 miR-1 is increased in pulmonary hypertension and downregulates Kv1.5 channels in rat pulmonary arteries J. Physiol. (Lond.) 2018 3' UTR SC209953
Klotho microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress PLoS ONE 3' UTR SC217236
KPNA4 Long noncoding RNA NEAT1 drives aggressive endometrial cancer progression via miR-361-regulated networks involving STAT3 and tumor microenvironment-related genes J. Exp. Clin. Cancer Res. 3' UTR SC217144
LTA4H Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA Scientific Reports 2, doi:10.1038/srep00639 3' UTR SC201507
LYPD3 Concurrent expression of C4.4A and Tenascin-C in tumor cells relates to poor prognosis of esophageal squamous cell carcinoma. International journal of oncology 3' UTR SC207891
LYPD3 C 4.4 A is associated with tumor budding and epithelial–mesenchymal transition of colorectal cancer Cancer Science 3' UTR SC207891
MADH7 The activation of microRNA-520h-associated TGF-β1/c-Myb/Smad7 axis promotes epithelial ovarian cancer progression Cell Death Dis 3' UTR SC215141
MADH7 Identification of a novel PPARß/d/miR-21-3p axis in UV-induced skin inflammation EMBO Mol Med 3' UTR SC215141
MADH7 miR-1269 promotes metastasis and forms a positive feedback loop with TGF-[beta] Nature Communications 3' UTR SC215141
MAPKAPK2 Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis Molecular Biology of the Cell 3' UTR SC215446
MCP1 miR-98 and let-7g* protect the blood-brain barrier under neuroinflammatory conditions J. Cereb. Blood Flow Metab. 3' UTR SC205217
MEK1 MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner Journal of Hematology & Oncology 3' UTR SC211301
MET An integrated genomic analysis of papillary renal cell carcinoma type 1 uncovers the role of focal adhesion and extracellular matrix pathways Molecular Oncology 3' UTR SC218300
MIEN1 MicroRNA-940 suppresses prostate cancer migration and invasion by regulating MIEN1 Mol. Cancer 3' UTR SC205280
MIR22 Improved protein expression in HEK293 cells by over-expressing miR-22 and knocking-out its target gene, HIPK1 N Biotechnol 3' UTR SC400286
MIR27B MicroRNA-27b Targets Gremlin 1 to Modulate Fibrotic Responses in Pulmonary Cells J. Cell. Biochem. 3' UTR SC400303
MIR371 SMAR1 binds to T(C/G) repeat and inhibits tumor progression by regulating miR-371-373 cluster Sci Rep 3' UTR SC400367
MIR372 SMAR1 binds to T(C/G) repeat and inhibits tumor progression by regulating miR-371-373 cluster Sci Rep 3' UTR SC400368
MIR373 SMAR1 binds to T(C/G) repeat and inhibits tumor progression by regulating miR-371-373 cluster Sci Rep 3' UTR SC400369
MIRLET7c A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells Carcinogenesis, Aug 2013; 10.1093/carcin/bgt255. 3' UTR SC400005
MSH2 Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway Mol. Carcinog. 3' UTR SC203467
MSH3 Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway Mol. Carcinog. 3' UTR SC211522
MTA1 The E3 ligase for metastasis associated 1 protein, TRIM25, is targeted by microRNA-873 in hepatocellular carcinoma Exp. Cell Res. 3' UTR SC207007
MTOR An integrated genomic analysis of papillary renal cell carcinoma type 1 uncovers the role of focal adhesion and extracellular matrix pathways Molecular Oncology 3' UTR SC211383
mtTFA Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM) Biochim. Biophys. Acta 3' UTR SC212176
MYB MicroRNA-150 Expression Induces Myeloid Differentiation of Human Acute Leukemia Cells and Normal Hematopoietic Progenitors PLoS One. 2013 Sep 24;8(9):e75815 3' UTR SC213071
MYCN miR-15a-5p, miR-15b-5p, and miR-16-5p inhibit tumor progression by directly targeting MYCN in neuroblastoma Mol Oncol 3' UTR SC211080
Myeloid zinc finger 1 Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1 Oncogenesis 3' UTR SC201770
NCAPH2 Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters Science Advances 3' UTR SC201070
NCL Nucleolin Mediates MicroRNA-directed CSF-1 mRNA Deadenylation but Increases Translation of CSF-1 mRNA Mol. Cell. Proteomics, Jun 2013; 12: 1661 - 1677. 3' UTR SC206187
NF-kB p65 Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism Mol Ther Oncolytics 3' UTR SC209996
NF-kB p65 Sevoflurane exerts protective effects on liver ischemia/reperfusion injury by regulating NFKB3 expression via miR‑9‑5p Exp Ther Med 3' UTR SC209996
NF-kB p65 MicroRNA expression profiling of human blood monocyte subsets highlights functional differences Immunology 3' UTR SC209996
NOD2 miRNAs Affect the Expression of Innate and Adaptive Immunity Proteins in Celiac Disease Am. J. Gastroenterol. July 2014 3' UTR SC213503
NUP98 ADAR2/miR-589-3p axis controls glioblastoma cell migration/invasion Nucleic Acids Res. 3' UTR SC212817
Oct4 Regulation of miRNA biogenesis and histone modification by K63-polyubiquitinated DDX17 controls cancer stem-like features Cancer Res. 3' UTR SC203486
ORP150 miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration Sci Rep 3' UTR SC214544
p21 Barrier Function of the Repaired Skin Is Disrupted Following Arrest of Dicer in Keratinocytes Mol. Ther. 3' UTR SC215244
p27 KIP 1 In Vitro and In Vivo Activity of a Novel Locked Nucleic Acid (LNA)-Inhibitor-miR-221 against Multiple Myeloma Cells PLOS ONE, Feb 2014. 3' UTR SC214055
P2RX1 Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse Blood 3' UTR SC213589
P2RX1 Genetic and functional analysis of human P2X5 reveals a distinct pattern of exon 10 polymorphism with predominant expression of the nonfunctional receptor isoform. Molecular pharmacology 3' UTR SC213589
P2RX7 Diphenyleneiodonium enhances P2X7 dependent non-opsonized phagocytosis and suppresses inflammasome activation via blocking CX43-mediated ATP leakage. Pharmacological research 3' UTR SC213607
P2RX7 Distinct shear-induced Ca 2+ signaling in the left and right atrial myocytes: Role of P2 receptor context. Journal of molecular and cellular cardiology 3' UTR SC213607
P2RX7 P2X 4 Assembles with P2X 7 and Pannexin-1 in Gingival Epithelial Cells and Modulates ATP-induced Reactive Oxygen Species Production and Inflammasome Activation PLoS ONE 3' UTR SC213607
PAPPA2 PAPPA2 , an Enzyme That Cleaves an Insulin-Like Growth-Factor-Binding Protein, Is a Candidate Gene for a Quantitative Trait Locus Affecting Body Size in Mice 3' UTR SC205384
PARP1 Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b eNeuro 3' UTR SC209859
PARP1 microRNA 223 Is Upregulated in the Multistep Progression of Barrett's Esophagus and Modulates Sensitivity to Chemotherapy by Targeting PARP1 Clin. Cancer Res., Aug 2013; 19: 4067 - 4078. 3' UTR SC209859
PBP Increased expression of miR-23a mediates a loss of expression in the RAF kinase inhibitor protein RKIP Cancer Research 3' UTR SC209990
PCBP1 MicroRNA-490 regulates lung cancer metastasis by targeting poly r(C)-binding protein 1 Tumour Biol. 3' UTR SC205517
PCBP1 Poly r(C) binding protein (PCBP) 1 is a negative regulator of thyroid carcinoma Am J Transl Res 3' UTR SC205517
PCBP1 Poly r(C) binding protein is post-transcriptionally repressed by MiR-490-3p to potentiate squamous cell carcinoma Tumour Biol. 3' UTR SC205517
PCBP1 Poly r (C) binding protein (PCBP) 1 is a negative regulator of thyroid carcinoma American Journal of Translational Research 3' UTR SC205517
PDCD4 Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival Oncogenesis 3' UTR SC217111
PDIA6 Interplay Between the Oxidoreductase PDIA6 and microRNA-322 Controls the Response to Disrupted Endoplasmic Reticulum Calcium Homeostasis Sci Signal 3' UTR SC210773
PFKM MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1 Nat Commun 3' UTR SC209129
PI 3 Kinase catalytic subunit alpha MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway FASEB J., Feb 2014. 3' UTR SC204844
PI 3 Kinase catalytic subunit gamma MicroRNA-204-3p inhibits lipopolysaccharide-induced cytokines in familial Mediterranean fever via the phosphoinositide 3-kinase γ pathway Rheumatology (Oxford) 2017 3' UTR SC216338
PIM1 Antiproliferative potential of miR-33a in laryngeal cancer Hep-2 cells via targeting PIM1 Head Neck 3' UTR SC214258
PIM1 miR-33a is a tumor suppressor microRNA that is decreased in prostate cancer Oncotarget 3' UTR SC214258
PITX2 Rare FOXC1 variants in congenital glaucoma: identification of translation regulatory sequences European Journal of Human Genetics 3' UTR SC209282
PLGF Erythropoietin mediated expression of Placenta Growth Factor is regulated via activation of hypoxia inducible factor -1a and post-transcriptionally by mir214 in Sickle Cell Disease Biochem. J. 3' UTR SC210960
PNPLA2 Micro RNA-124a Regulates Lipolysis via Adipose Triglyceride Lipase and Comparative Gene Identification 58 Int J Mol Sci 3' UTR SC205323
POLD3 Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway Mol. Carcinog. 3' UTR SC217193
PPAR gamma Macrophages exposed to HIV viral protein disrupt lung epithelial cell integrity and mitochondrial bioenergetics via exosomal microRNA shuttling Cell Death Dis 3' UTR SC202417
PREB Foot-and-Mouth Disease Virus 3A Hijacks Sar1 and Sec12 for ER Remodeling in a COPII-Independent Manner Viruses 3' UTR SC209101
PREX1 IDENTIFICATION OF THE Rac-GEF P-REX1 AS AN ESSENTIAL MEDIATOR OF ErbB SIGNALING IN BREAST CANCER 3' UTR SC215722
PRKRA MicroRNA-122 Inhibits the Production of Inflammatory Cytokines by Targeting the PKR Activator PACT in Human Hepatic Stellate Cells PLoS ONE 3' UTR SC208870
PRMT9 PRMT5: A novel regulator of Hepatitis B virus replication and an arginine methylase of HBV core PLoS ONE 3' UTR SC201605
Prostaglandin dehydrogenase 1 ?-3 polyunsaturated fatty acids upregulate 15-PGDH expression in cholangiocarcinoma cells by inhibiting miR-26a/b expression Cancer Res. 3' UTR SC216485
PSAP Prosaposin is a regulator of progranulin levels and oligomerization Nat Commun 3' UTR SC212847
PSMA6 Proteasome subunit alpha type-6 protein is posttranscriptionally repressed by the microRNA-4490 in diabetic nephropathy Biosci. Rep. 3' UTR SC201979
PTGR1 Novel involvement of miR-522-3p in high-mobility group box 1-induced prostaglandin reductase 1 expression and reduction of phagocytosis Biochim. Biophys. Acta 3' UTR SC201488
PTGS2 Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition Oncotarget 3' UTR SC219115
PTK2 MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells Anticancer Agents Med Chem, Jan 2014. 3' UTR SC212185
PTPN1 TRIM18-Regulated STAT3 Signaling Pathway via PTP1B Promotes Renal Epithelial–Mesenchymal Transition, Inflammation, and Fibrosis in Diabetic Kidney Disease Frontiers in Physiology 3' UTR SC216694
PTPN1 Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo Parkinson's Disease 3' UTR SC216694
PTPN1 Targeting pancreatic islet PTP1B improves islet graft revascularization and transplant outcomes. Science translational medicine 3' UTR SC216694
PTPN1 LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition Cell Research 3' UTR SC216694
PTPN1 HER2 Phosphorylates and Destabilizes Pro-Apoptotic PUMA, Leading to Antagonized Apoptosis in Cancer Cells PLoS ONE 3' UTR SC216694
RAB9A An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia The Journal of Clinical Investigation 3' UTR SC204046
RANTES Oncosuppressive miRNAs loaded in lipid nanoparticles potentiate targeted therapies in BRAF-mutant melanoma by inhibiting core escape pathways of resistance Oncogene 3' UTR SC210875
RANTES miR-98 and let-7g* protect the blood-brain barrier under neuroinflammatory conditions J. Cereb. Blood Flow Metab. 3' UTR SC210875
RASGRF2 The Use of Knockout Mice Reveals a Synergistic Role of the Vav1 and Rasgrf2 Gene Deficiencies in Lymphomagenesis and Metastasis PLoS ONE 3' UTR SC204901
RASSF1 Excess of a Rassf1-targeting microRNA, miR-193a-3p, perturbs cell division fidelity Br. J. Cancer 3' UTR SC210114
RASSF8 MicroRNA-181b promotes osteosarcoma cell proliferation, invasion and migration in vitro via targeting RASSF8 Int J Clin Exp Pathol 3' UTR SC210298
REL MicroRNA-365a-3p inhibits c-Rel-mediated NF-κB signaling and the progression of pancreatic cancer Cancer Lett. 3' UTR SC206857
ROCK1 Long noncoding RNA NEAT1 drives aggressive endometrial cancer progression via miR-361-regulated networks involving STAT3 and tumor microenvironment-related genes J. Exp. Clin. Cancer Res. 3' UTR SC215786
ROCK2 Inhibition of Rho-Associated Kinase Suppresses Medulloblastoma Growth Cancers 3' UTR SC216436
ROCK2 Rho-associated kinase is a therapeutic target in neuroblastoma Proceedings of the National Academy of Sciences of the United States of America 3' UTR SC216436
ROCK2 Down-regulation of the Rho GTPase signaling pathway is involved in the microRNA-138 mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma 3' UTR SC216436
RPS4Y1 Identification of Ribosomal Protein S4, Y-Linked 1 as a cyclosporin A plus corticosteroid resistance gene. Journal of autoimmunity 3' UTR SC200290
RYR3 Extracellular calcium-sensing receptor is critical in hypoxic pulmonary vasoconstriction. Antioxidants & redox signaling 3' UTR SC210746
SAYSD1 SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum Cell reports 3' UTR SC214181
SERCA2 miR-25 Tough Decoy enhances cardiac function in heart failure Molecular Therapy 3' UTR SC210032
SERPINA1 miR-199a-5p Silencing Regulates the Unfolded Protein Response in COPD and a1 Antitrypsin Deficiency Am. J. Respir. Crit. Care Med. Dec 2013. 3' UTR SC216088
SERPINA1 Isolation and identification of cell-specific microRNAs targeting a messenger RNA using a biotinylated anti-sense oligonucleotide capture affinity technique Nucleic Acids Res., Apr 2013; 41: e71. 3' UTR SC216088
SHMT2 miR-615-5p prevents proliferation and migration through negatively regulating serine hydromethyltransferase 2 (SHMT2) in hepatocellular carcinoma Tumour Biol. 3' UTR SC207647
SLC16A7 MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG Nature chemical biology 3' UTR SC217291
SLC2A4 Neurolytic celiac plexus block enhances skeletal muscle insulin signaling and attenuates insulin resistance in GK rats Experimental and Therapeutic Medicine 3' UTR SC214541
SLC2A4 MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue Journal of Diabetes Research 3' UTR SC214541
SLC2A4 miRNA-93 Inhibits GLUT4 and Is Overexpressed in Adipose Tissue of Polycystic Ovary Syndrome Patients and Women With Insulin Resistance Diabetes 3' UTR SC214541
SLC2A4 Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity. Diabetes/metabolism research and reviews 3' UTR SC214541
SLC5A2 Dual-Target Compounds against Type 2 Diabetes Mellitus : Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors Pharmaceuticals 3' UTR SC202921
SLC5A2 Pharmacological evaluation of HM41322, a novel SGLT1/2 dual inhibitor, in vitro and in vivo The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology 3' UTR SC202921
SLC5A2 SHR3824, a novel selective inhibitor of renal sodium glucose cotransporter 2, exhibits antidiabetic efficacy in rodent models Acta Pharmacologica Sinica 3' UTR SC202921
SLPI The Estrogen-Induced miR-19 Downregulates Secretory Leucoprotease Inhibitor Expression in Monocytes J Innate Immun 3' UTR SC201857
SNAIL Extracellular vesicle-encapsulated miR-30e suppresses cholangiocarcinoma cell invasion and migration via inhibiting epithelial-mesenchymal transition Oncotarget 3' UTR SC210383
SNAIL MicroRNA-153 inhibits tumor progression in esophageal squamous cell carcinoma by targeting SNAI1 Tumour Biol. 3' UTR SC210383
SOCS3 Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 Diabetes Diabetes, Feb 2013; 62: 457 - 465. 3' UTR SC215826
SOD2 Glucose-sensing microRNA-21 disrupts ROS homeostasis and impairs antioxidant responses in cellular glucose variability Cardiovasc Diabetol 3' UTR SC209718
SOD2 Hepatitis C and Alcohol Exacerbate Liver Injury by Suppression of FOXO3 Am. J. Pathol. 1803-14 3' UTR SC209718
SOX11 Dual regulatory effects of PI(4,5)P 2 on TREK-2 K + channel through antagonizing interaction between the alkaline residues (K 330 and R 355-357 ) in the cytosolic C-terminal helix The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology 3' UTR SC222741
SOX11 Identification of critical amino acids in the proximal C-terminal of TREK-2 K + channel for activation by acidic pH i and ATP-dependent inhibition. Pflugers Archiv : European journal of physiology 3' UTR SC222741
SOX11 Inhibition of TREK-2 K(+) channels by PI(4,5)P2: an intrinsic mode of regulation by intracellular ATP via phosphatidylinositol kinase. Pflugers Archiv : European journal of physiology 3' UTR SC222741
SOX2 Regulation of miRNA biogenesis and histone modification by K63-polyubiquitinated DDX17 controls cancer stem-like features Cancer Res. 3' UTR SC212702
SOX2 Human antigen R binding and regulation of SOX2 mRNA in human mesenchymal stem cells Mol. Pharmacol. 3' UTR SC212702
SOX2 Condensin confers the longitudinal rigidity of chromosomes Nat. Cell Biol. 3' UTR SC212702
SOX2 Therapeutic targeting of CBP/ß-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin Scientific reports 3' UTR SC212702
SPHK1 Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo Scientific Reports 3' UTR SC203800
SPHK1 MicroRNA-1 Is Decreased by Hypoxia and Contributes to the Development of Pulmonary Vascular Remodeling via Regulation of Sphingosine Kinase 1 Am. J. Physiol. Lung Cell Mol. Physiol.2017 3' UTR SC203804
STAMBP microRNA-378a-5p iS a novel positive regulator of melanoma progression Oncogenesis 3' UTR SC208375
STIM1 Targeting the Ca(2+) Sensor STIM1 by Exosomal Transfer of Ebv-miR-BART13-3p is Associated with Sjögren's Syndrome EBioMedicine 3' UTR SC214586
TAGLN2 Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer Oncogene 3' UTR SC208903
TERT A novel method for banking stem cells from human exfoliated deciduous teeth: lentiviral TERT immortalization and phenotypical analysis Stem Cell Research & Therapy 3' UTR SC207505
THBS1 Thrombospondin-1 overexpression stimulates loss of Smad4 and accelerates malignant behavior via TGF-β signal activation in pancreatic ductal adenocarcinoma Translational Oncology 3' UTR SC217830
THBS1 FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1 International Journal of Oncology 3' UTR SC217830
THBS2 Monoclonal antibodies to murine thrombospondin-1 and thrombospondin-2 reveal differential expression patterns in cancer and low antigen expression in normal tissues. Experimental cell research 3' UTR SC217544
TIAM1 Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3 and KIT driven Leukemogenesis Cell reports 3' UTR SC217254
TJP1 Macrophages exposed to HIV viral protein disrupt lung epithelial cell integrity and mitochondrial bioenergetics via exosomal microRNA shuttling Cell Death Dis 3' UTR SC214630
TJP1 Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1 Oncogene 3' UTR SC214630
TLR9 Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis Frontiers in Immunology 3' UTR SC201161
TLR9 Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Molecular pharmacology 3' UTR SC201161
TLR9 MORPHINE MODULATION OF TOLL LIKE RECEPTORS IN MICROGLIAL CELLS POTENTIATES NEUROPATHOGENESIS IN A HIV -1 MODEL OF CO-INFECTION WITH PNEUMOCOCCAL PNEUMONIAE The Journal of neuroscience : the official journal of the Society for Neuroscience 3' UTR SC201161
TMED3 TMED3 promotes cell proliferation and motility in breast cancer and is negatively modulated by miR-188-3p Cancer Cell Int. 3' UTR SC208836
TMEM16A MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology Nat Commun 3' UTR SC215210
TNF alpha MicroRNA-181c Inhibits Interleukin-6-mediated Beta Cell Apoptosis by Targeting TNF-α Expression Molecules 3' UTR SC209984
TNF alpha Regulation of proinflammatory genes by the circulating microRNA hsa-miR-939 Sci Rep 3' UTR SC209984
TNFRSF6B Anti‐oral cancer effects of triptolide by downregulation of DcR3 in vitro, in vivo, and in preclinical patient‐derived tumor xenograft model Head & Neck 3' UTR SC200927
TTF1 Clinicopathological characteristics of primary peritoneal epithelioid mesothelioma of clear cell type Medicine 3' UTR SC204934
TWIST1 MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist J. Exp. Clin. Cancer Res. 3' UTR SC209156
U2AF2 Differential regulation of sFlt-1 splicing by U2AF65 and JMJD6 in placental-derived and endothelial cells Bioscience Reports 3' UTR SC208640
UBL5 The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells Journal of Molecular Cell Biology 3' UTR SC201092
UCP2 Dynamic regulation of uncoupling protein 2 expression by microRNA-214 in hepatocellular carcinoma Biosci. Rep 3' UTR SC204466
USP42 Dengue NS5 modulates expression of miR‐590 to regulate ubiquitin‐specific peptidase 42 in human microglia FASEB bioAdvances 3' UTR SC212166
USP42 Dengue NS 5 modulates expression of miR‐590 to regulate Ubiquitin specific peptidase 42 in human microglia FASEB BioAdvances 3' UTR SC212166
VEGFA Calreticulin regulates vascular endothelial growth factor-A mRNA stability in gastric cancer cells PLoS ONE 3' UTR SC217125
VEGFA Long noncoding RNA NEAT1 drives aggressive endometrial cancer progression via miR-361-regulated networks involving STAT3 and tumor microenvironment-related genes J. Exp. Clin. Cancer Res. 3' UTR SC217124
VEGFA miR-126-3p down-regulation contributes to dabrafenib acquired resistance in melanoma by up-regulating ADAM9 and VEGF-A J. Exp. Clin. Cancer Res. 3' UTR SC217124
VEGFA miR-126-3p down-regulation contributes to dabrafenib acquired resistance in melanoma by up-regulating ADAM9 and VEGF-A J. Exp. Clin. Cancer Res. 3' UTR CW303621
VEGFA Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer Oncotarget 3' UTR SC217124
VPS4A Identification of a New Target of miR-16, Vacuolar Protein Sorting 4a PLoS ONE July 2014 3' UTR SC209710
WIF1 The Wnt Receptor Ryk Plays a Role in Mammalian Planar Cell Polarity Signaling The Journal of Biological Chemistry 3' UTR SC209449
WNT3A AurkA controls self-renewal of breast cancer-initiating cells promoting wnt3a stabilization through suppression of miR-128 Sci Rep 3' UTR SC216481
WNT7A Exosomes derived from PM2.5‑treated lung cancer cells promote the growth of lung cancer via the Wnt3a/β‑catenin pathway. Oncology reports 3' UTR SC205065
WNT7A Long noncoding RNA NEAT1 drives aggressive endometrial cancer progression via miR-361-regulated networks involving STAT3 and tumor microenvironment-related genes J. Exp. Clin. Cancer Res. 3' UTR SC205065
WNT7A A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice Stem Cells International 3' UTR SC205065
ZGRF1 Protocol for Purification of Human ZGRF1 and Its Regulatory Function on RAD51-Mediated D-Loop Formation STAR Protocols 3' UTR SC202466
ZGRF1 The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells Cell reports 3' UTR SC202466